Blossom is the leader of the Powerpuff Girls. Strong, determined and thoughtful, she tries hard not to be all work and no play, but sometimes gets bossy with Buttercup and Bubbles without meaning to. She also tries to stop arguments in the group.
Once Professor Utonium's lab assistant, Mojo Jojo was accidentally transformed from a normal monkey into the Powerpuff Girls' enemy. As well as fighting the girls though, Mojo sometimes teams up with them when it benefits him.
What the dim-witted Mayor of Townsville lacks in brains, he makes up for in heart. He's deeply protective of Townsville, if for no other reason than it's home to the finest pickles he's ever tasted.
Bubbles is the softest, sweetest and cutest Powerpuff Girl, but that doesn't mean she's a pushover. Sometimes bad guys and monsters have a tendency to dismiss her, but they're the ones who are always sorry! One of Bubbles' abilities is her hyper sonic scream.
Buttercup is a tough, hot-headed tomboy and doesn't have time for plans - when evil emerges, she's ready. Buttercup is the only Powerpuff Girl without special powers (Blossom has ice breath, and Bubbles has a gift of languages).
Professor Utonium created The Powerpuff Girls by accidentally infusing his "Perfect Girl Concoction" with a mysterious substance called "Chemical X". He's a brilliant scientist who now acts as the girls' father (including making their lunches and cheering them up).